XCW LAB / PEOPLE
Rui Mao
毛瑞
Assistant Researcher
School of Environmental and Sustainable Engineering
Rui Mao earned a PhD in Biochemical Engineering from the Institute of Process Engineering, Chinese Academy of Sciences. He has more than ten years of experience developing PCR, isothermal amplification and microfluidic technologies for rapid nucleic acid biomarker detection. His work includes 11 granted Chinese invention patents, one European invention patent and more than 20 papers, including 15 SCI papers as first or last corresponding author. His current research focuses on new nucleic acid diagnostic technologies, system integration and product development for pathogens, cancer and environmental applications.
Research interests
Environmental pathogen identification and surveillance
Ultrasensitive molecular recognition and signal amplification
Education & experience
- 2013–2018 · Institute of Process Engineering, Chinese Academy of Sciences · PhD · Biochemical Engineering
Selected work
- Paper · 2026
Optimization of loop-mediated isothermal amplification harnessing a novel primer design targeting at short DNA sequence ↗
Zhang Y, Ouyang G, Zheng D, Chen X, Mao R*. · Microchemical Journal
- Paper · 2022
Closed dumbbell mediated isothermal amplification of nucleic acids for DNA diagnostic assays ↗
Mao R*, Wang T, Zhao Y, Wu X, Zhang S, Cai T*. · Talanta
- Paper · 2026
Establishment of closed dumbbell mediated isothermal amplification assay for rapid and simple detection of Streptococcus agalactiae (GBS) ↗
Zhang Y, Chen X, Zhong Y, Guo F, Chen Y*, Ouyang G*, Mao R*. · Microchemical Journal
- Paper · 2025
Development and validation of on-site authentication of Gadus morhua using closed dumbbell mediated isothermal amplification ↗
Jiang H, Chen X, Mao R*. · Journal of Food Composition and Analysis
- Paper · 2024
Development of closed dumbbell mediated isothermal amplification assay for rapid and on-site detection of Vibrio parahaemolyticus ↗
Zhang Y, Ouyang G, Chen X, Guo F, Mao R*. · Microchemical Journal
- Patent · 2022
恒温条件下合成核酸的方法及试剂盒和应用
毛瑞，王天祚，蔡挺. · 国家知识产权局
中国发明专利号：ZL202110473121.8
- Patent · 2022
非对称环介导恒温条件下合成核酸的方法及试剂盒和应用
毛瑞，吴欣瑶，蔡挺，缪青. · 国家知识产权局
中国发明专利号：ZL202111543952.4
- Patent · 2024
非诊断目的的恒温条件下合成核酸的方法及试剂盒和应用
毛瑞，赵月，蔡挺，缪青. · 国家知识产权局
中国发明专利号：ZL202210120186.9